Overview

Quick reference

Summary

Carotid artery stenting (CAS) is the endovascular alternative to endarterectomy for internal carotid stenosis selected for revascularisation, symptomatic or asymptomatic. A self-expanding stent is placed across the bifurcation under embolic protection, reached through the femoral or radial artery or, in transcarotid artery revascularisation (TCAR), through the common carotid artery under flow reversal. Selection rests on the patient's procedural risk and on the anatomy of the aortic arch, the lesion and the neck on CT angiography (CTA), which together show whether stenting is suitable and by which route. The procedure is done under dual antiplatelet therapy, with prevention of bradycardia and hypotension during balloon inflation and observation for cerebral hyperperfusion afterwards. Heavily calcified lesions and irradiated or otherwise hostile necks need particular planning.

Takeaways

  1. 1

    Choose transfemoral, transradial or transcarotid access from CTA of the arch, vessel tortuosity, calcium and neck anatomy.

  2. 2

    Start dual antiplatelet therapy before every carotid stenting, with a clopidogrel loading dose when there is no time for pretreatment.

  3. 3

    When in-stent restenosis needs treatment, choose repeat stenting over balloon angioplasty alone.

Start here

  1. Carotid Artery Stenting: JACC State-of-the-Art ReviewWhite 2022 · J Am Coll Cardiol
  2. Predictors of Stroke, Myocardial Infarction or Death within 30 Days of Carotid Artery Stenting: Results from the International Carotid Stenting StudyDoig 2016 · Eur J Vasc Endovasc Surg
  3. Editor's Choice - European Society for Vascular Surgery (ESVS) 2023 Clinical Practice Guidelines on the Management of Atherosclerotic Carotid and Vertebral Artery DiseaseNaylor 2023 · Eur J Vasc Endovasc Surg
  4. Cumulative incidence of restenosis in the endovascular treatment of extracranial carotid artery stenosis: a meta-analysisClavel 2019 · J Neurointerv Surg
  5. Results of the ROADSTER multicenter trial of transcarotid stenting with dynamic flow reversalKwolek 2015 · J Vasc Surg · landmark
  6. Association of Transcarotid Artery Revascularization vs Transfemoral Carotid Artery Stenting With Stroke or Death Among Patients With Carotid Artery StenosisSchermerhorn 2019 · JAMA · pivotal
Back to overviewCarotid diseaseThe carotid diseases a neurointerventionalist treats, how they are graded and imaged, and which page covers each decision.

Carotid stenting and TCAR

Healthcare professionals · Updated 1 Nov 2026 · G. Kalarakis

Carotid diseaseChapter 3 of 3
Quick reference

Summary

Carotid artery stenting (CAS) is the endovascular alternative to endarterectomy for internal carotid stenosis selected for revascularisation, symptomatic or asymptomatic. A self-expanding stent is placed across the bifurcation under embolic protection, reached through the femoral or radial artery or, in transcarotid artery revascularisation (TCAR), through the common carotid artery under flow reversal. Selection rests on the patient's procedural risk and on the anatomy of the aortic arch, the lesion and the neck on CT angiography (CTA), which together show whether stenting is suitable and by which route. The procedure is done under dual antiplatelet therapy, with prevention of bradycardia and hypotension during balloon inflation and observation for cerebral hyperperfusion afterwards. Heavily calcified lesions and irradiated or otherwise hostile necks need particular planning.

Takeaways

  1. 1

    Choose transfemoral, transradial or transcarotid access from CTA of the arch, vessel tortuosity, calcium and neck anatomy.

  2. 2

    Start dual antiplatelet therapy before every carotid stenting, with a clopidogrel loading dose when there is no time for pretreatment.

  3. 3

    When in-stent restenosis needs treatment, choose repeat stenting over balloon angioplasty alone.

Start here

  1. Carotid Artery Stenting: JACC State-of-the-Art ReviewWhite 2022 · J Am Coll Cardiol
  2. Predictors of Stroke, Myocardial Infarction or Death within 30 Days of Carotid Artery Stenting: Results from the International Carotid Stenting StudyDoig 2016 · Eur J Vasc Endovasc Surg
  3. Editor's Choice - European Society for Vascular Surgery (ESVS) 2023 Clinical Practice Guidelines on the Management of Atherosclerotic Carotid and Vertebral Artery DiseaseNaylor 2023 · Eur J Vasc Endovasc Surg
  4. Cumulative incidence of restenosis in the endovascular treatment of extracranial carotid artery stenosis: a meta-analysisClavel 2019 · J Neurointerv Surg
  5. Results of the ROADSTER multicenter trial of transcarotid stenting with dynamic flow reversalKwolek 2015 · J Vasc Surg · landmark
  6. Association of Transcarotid Artery Revascularization vs Transfemoral Carotid Artery Stenting With Stroke or Death Among Patients With Carotid Artery StenosisSchermerhorn 2019 · JAMA · pivotal

Back to overviewCarotid diseaseThe carotid diseases a neurointerventionalist treats, how they are graded and imaged, and which page covers each decision.